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Query: PDS5B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PDS5B 0 2.872 0.400 -0.180 0.010 0.455 1.005 0.576

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PDS5B Phosphorylation S1257 0.679 0.856 _GHTAS(ph)ESDEQQWPEEK_
PDS5B Phosphorylation S1358 0.352 0.386 _AES(ph)PESSAIESTQST(ph)PQK_
PDS5B Phosphorylation S1383 0.499 0.305 _TPS(ph)PSQPK_
PDS5B Phosphorylation S1166 0.251 -0.039 _METVSNASSSSNPSS(ph)PGR_
PDS5B Phosphorylation S1283 -0.320 -0.086 _RLKEDILENEDEQNS(ph)PPK_
PDS5B Phosphorylation S1160 -0.554 _M(ox)ETVSNASS(ph)SSNPSS(ph)PGR_
PDS5B Ubiquitylation K212 -0.709 _NLNK(gl)QAYDLAK_
PDS5B Phosphorylation T1370 -0.515 -0.777 _AES(ph)PESSAIESTQST(ph)PQK_
PDS5B Phosphorylation S1369 -0.338 _AES(ph)PESSAIESTQS(ph)TPQK_

Background Information for PDS5B:


Pubmed-PDS5B »
Uniprot-PDS5B »
Biogrid-PDS5B »
ProteomicsDB-PDS5B »

Tumorportal-PDS5B »
COSMIC-PDS5B »
GenomeRNAi-PDS5B »
Genecards-PDS5B


Protein-protein Interactions for PDS5B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCZ Cat. description Hein, Mann, Cell 2015
Category members IP bait RAD21 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC1A Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait WAPAL Cat. description Hein, Mann, Cell 2015
Category members IP bait 12-Sep Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ANK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait APLNR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GYPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1467 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P2RX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAD21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC15A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC30A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PDS5B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring PDS5B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1856 CDCA5-PDS5A-RAD21-SMC1A-PDS5B-SMC3 complex Database 1.25
Category members Corum 5432 Sororin-cohesin complex Database 1.25


Categories featuring PDS5B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0000785 chromatin Database 2.59
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members GO Category GO:0007064 mitotic sister chromatid cohesion Database 0.03


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