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Query: PCYT1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PCYT1A 1 4.916 -0.890 0.640
PCYT1A 1 4.916 -0.890 0.640 1.645 1.375

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PCYT1A Phosphorylation S331 0.642 0.418 _SPS(ph)PSFR_
PCYT1A Ubiquitylation K228 0.196 _GYTAK(gl)ELNVSFINEK_
PCYT1A Phosphorylation T342 -1.306 0.087 _T(ph)SPPCSPANLSR_
PCYT1A Phosphorylation S343 -1.306 0.087 _TS(ph)PPCS(ph)PANLSR_
PCYT1A Phosphorylation S347 -1.095 -1.321 _TS(ph)PPCS(ph)PANLSR_

Background Information for PCYT1A:


Pubmed-PCYT1A »
Uniprot-PCYT1A »
Biogrid-PCYT1A »
ProteomicsDB-PCYT1A »

Tumorportal-PCYT1A »
COSMIC-PCYT1A »
GenomeRNAi-PCYT1A »
Genecards-PCYT1A


Protein-protein Interactions for PCYT1A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP170P1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP170 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPRC5C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IP6K3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NMNAT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM206 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PCYT1A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NA-bd_OB-fold IPR012340 4.37
Category members Cyt_trans-like IPR004821 0


Protein complexes (CORUM database) featuring PCYT1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PCYT1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0006656 phosphatidylcholine biosynthetic process Database 0.45
Category members GO Category GO:0042587 glycogen granule Database 0.44
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_711 REACTOME_SYNTHESIS_OF_PC 0 0.22
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0009058 biosynthetic process Database 0.11
Category members GO Category GO:0009628 response to abiotic stimulus Database 0.1
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_161 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_276 KEGG_GLYCEROPHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0004105 choline-phosphate cytidylyltransferase activity Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0006657 CDP-choline pathway Database 0
Category members GO Category GO:0008289 lipid binding Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0046474 glycerophospholipid biosynthetic process Database 0


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