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Query: PCGF6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PCGF6 0 -3.698 0.670 0.070 0.099 -0.103 0.347

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PCGF6 Phosphorylation S115 1.032 0.880 _LEGGRQDS(ph)EDEEER_
PCGF6 Ubiquitylation K234 -2.981 -2.972 _GLEVPKPAVPQPVPSSK(gl)GR_

Background Information for PCGF6:


Pubmed-PCGF6 »
Uniprot-PCGF6 »
Biogrid-PCGF6 »
ProteomicsDB-PCGF6 »

Tumorportal-PCGF6 »
COSMIC-PCGF6 »
GenomeRNAi-PCGF6 »
Genecards-PCGF6


Protein-protein Interactions for PCGF6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX7 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLHL22 Cat. description Hein, Mann, Cell 2015
Category members IP bait L3MBTL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NDEL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RING1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF526 Cat. description Hein, Mann, Cell 2015
Category members IP bait CARD8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CBX7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CORO6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait E2F6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MIER2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSME3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WBP2NL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PCGF6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Znf_RING IPR001841 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring PCGF6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PCGF6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0031519 PcG protein complex Database 0.62
Category members GO Category GO:0035102 PRC1 complex Database 0.62
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0046872 metal ion binding Database 0


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