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Query: PAWR

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PAWR 1 3.782 -0.550 -0.030 0.396 2.290

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PAWR Ubiquitylation K227 0.632 _YK(gl)STTSVSEEDVSSR_
PAWR Phosphorylation T230 0.494 _STT(ph)SVSEEDVSSR_
PAWR Phosphorylation S231 0.126 _STTS(ph)VSEEDVSSR_
PAWR Phosphorylation S233 0.241 _STTSVS(ph)EEDVSSR_

Background Information for PAWR:





Protein-protein Interactions for PAWR

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HMG20A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait HMG20A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKBIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCOC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PAWR

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PAWR

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 4039 PAR4-BACE1 complex Database 0


Categories featuring PAWR

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_880 PID_AR_PATHWAY 0 0.58
Category members GO Category GO:0051017 actin filament bundle assembly Database 0.47
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0043522 leucine zipper domain binding Database 0.15
Category members GO Category GO:0005884 actin filament Database 0.08
Category members GO Category GO:0042986 positive regulation of amyloid precursor protein biosynthetic process Database 0.05
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_734 PID_CERAMIDE_PATHWAY 0 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0030889 negative regulation of B cell proliferation Database 0
Category members GO Category GO:0042094 interleukin-2 biosynthetic process Database 0
Category members GO Category GO:0042130 negative regulation of T cell proliferation Database 0
Category members GO Category GO:0050860 negative regulation of T cell receptor signaling pathway Database 0


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