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Query: PARP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PARP2 0 -3.206 -0.150 -0.170 -0.627 -0.236

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PARP2 Phosphorylation S33 -0.845 -1.957 _RVNNGNTAPEDS(ph)SPAK_
PARP2 Phosphorylation S34 -1.168 -1.957 _RVNNGNTAPEDSS(ph)PAK_
PARP2 Ubiquitylation K91 0.459 _GK(gl)APVDPECTAK_

Background Information for PARP2:


Pubmed-PARP2 »
Uniprot-PARP2 »
Biogrid-PARP2 »
ProteomicsDB-PARP2 »

Tumorportal-PARP2 »
COSMIC-PARP2 »
GenomeRNAi-PARP2 »
Genecards-PARP2


Protein-protein Interactions for PARP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MSH6 Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMB5 Cat. description Hein, Mann, Cell 2015
Category members IP bait APLF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CETN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHD1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HMGN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LHX9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MACROD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAA40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF146 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPIN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR76 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XPC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XRCC6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF428 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PARP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WGR_domain IPR008893 0.03
Category members Poly(ADP-ribose)pol_reg_dom IPR004102 0
Category members Poly(ADP-ribose)pol_cat_dom IPR012317 0


Protein complexes (CORUM database) featuring PARP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PARP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members Pathway Pathway_881 PID_TELOMERASE_PATHWAY 0 2.64
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006284 base-excision repair Database 0.04
Category members Pathway Pathway_334 KEGG_BASE_EXCISION_REPAIR 0 0
Category members GO Category GO:0003950 NAD+ ADP-ribosyltransferase activity Database 0
Category members GO Category GO:0006471 protein ADP-ribosylation Database 0


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