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Query: PAPD5

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PAPD5 2 4.540 0.940 -0.220 0.000 0.344

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PAPD5 Phosphorylation S610 2.432 1.764 _VGS(ph)QDVSLESSQAVGK_

Background Information for PAPD5:


Pubmed-PAPD5 »
Uniprot-PAPD5 »
Biogrid-PAPD5 »
ProteomicsDB-PAPD5 »

Tumorportal-PAPD5 »
COSMIC-PAPD5 »
GenomeRNAi-PAPD5 »
Genecards-PAPD5


Protein-protein Interactions for PAPD5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C20orf43 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP152 Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAPD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0020 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPAN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL37A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3HAV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PAPD5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Nucleotidyltransferase IPR002934 0.13
Category members PAP_assoc IPR002058 0


Protein complexes (CORUM database) featuring PAPD5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PAPD5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0071044 histone mRNA catabolic process Database 0.35
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0003887 DNA-directed DNA polymerase activity Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0016779 nucleotidyltransferase activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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