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Query: NUP153

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NUP153 1 5.649 -0.870 1.040
NUP153 1 5.649 -0.870 1.040 -0.093 0.412 0.267

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NUP153 Phosphorylation S547 1.532 1.480 _VQMTS(ph)PSSTGSPMFK_
NUP153 Phosphorylation S192 0.745 1.127 _AS(ph)DKDITVSK_
NUP153 Phosphorylation S664 2.006 0.984 _IDSVAAQPTATS(ph)PVVYTR_
NUP153 Phosphorylation S645 0.720 _EGSVLDILKS(ph)PGFASPK_
NUP153 Phosphorylation S209 0.080 0.335 _NTSLPPLWS(ph)PEAER_
NUP153 Ubiquitylation K48 0.272 _VTESVK(gl)NIVPGWLQR_
NUP153 Phosphorylation S560 0.248 0.051 _FSS(ph)PIVK_
NUP153 Ubiquitylation K1087 -0.304 -0.185 _SSFNLGTIETK(gl)SASVAPFTCK_
NUP153 Phosphorylation S1494 -0.436 _NVFSSSGTSFS(ph)GRK_
NUP153 Ubiquitylation K1102 -0.308 -0.451 _TSEAK(gl)KEEMPATK_
NUP153 Phosphorylation T619 -0.625 _KT(ph)PPEDCEGPFRPAEILK_
NUP153 Ubiquitylation K15 0.265 -0.926 _(ac)ASGAGGVGGGGGGK(gl)IR_
NUP153 Ubiquitylation K263 -0.455 -1.080 _TSQLGDSPFYPGK(gl)TTYGGAAAAVR_
NUP153 Ubiquitylation K1004 -0.910 -1.408 _FGVSSESKPEEVK(gl)K_
NUP153 Ubiquitylation K1192 -1.547 -1.459 _STFSFSMTKPSEK(gl)ESEQPAK_
NUP153 Ubiquitylation K1188 -1.266 -1.535 _STFSFSMTK(gl)PSEKESEQPAK_
NUP153 Ubiquitylation K644 0.023 _EGSVLDILK(gl)SPGFASPK_
NUP153 Ubiquitylation K724 -0.298 _DTAK(gl)QTGIETPNK_
NUP153 Ubiquitylation K999 -0.710 _FGVSSESK(gl)PEEVKK_
NUP153 Ubiquitylation K1097 0.179 _SASVAPFTCK(gl)TSEAK_
NUP153 Ubiquitylation K1137 -0.654 _TEEK(gl)QQEPVTSTSLVFGK_
NUP153 Ubiquitylation K1152 -0.292 _TEEKQQEPVTSTSLVFGKK(gl)_

Background Information for NUP153:


Pubmed-NUP153 »
Uniprot-NUP153 »
Biogrid-NUP153 »
ProteomicsDB-NUP153 »

Tumorportal-NUP153 »
COSMIC-NUP153 »
GenomeRNAi-NUP153 »
Genecards-NUP153


Protein-protein Interactions for NUP153
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP107 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP214 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEH1L Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015
Category members IP bait G3BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KPNA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUSAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SREK1IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NUP153
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RanBP2 IPR001876 0.18


Protein complexes (CORUM database) featuring NUP153
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NUP153
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members Pathway Pathway_1310 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS 0 7.24
Category members Pathway Pathway_1311 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY 0 7.24
Category members Pathway Pathway_1206 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS 0 6.87
Category members GO Category GO:0005643 nuclear pore Database 6.58
Category members Pathway Pathway_878 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 0 6.53
Category members Pathway Pathway_886 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT 0 5.93
Category members GO Category GO:0010827 regulation of glucose transport Database 5.83
Category members GO Category GO:0007077 mitotic nuclear envelope disassembly Database 5.8
Category members Pathway Pathway_120 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN 0 5.24
Category members Pathway Pathway_887 REACTOME_METABOLISM_OF_NON_CODING_RNA 0 4.38
Category members GO Category GO:0008645 hexose transport Database 4.15
Category members Pathway Pathway_98 REACTOME_GLUCOSE_TRANSPORT 0 3.58
Category members Pathway Pathway_689 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 0 3.51
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0017056 structural constituent of nuclear pore Database 2.89
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0051292 nuclear pore complex assembly Database 2.26
Category members GO Category GO:0015758 glucose transport Database 2.09
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0044615 nuclear pore nuclear basket Database 1.35
Category members GO Category GO:0034399 nuclear periphery Database 1.34
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0042405 nuclear inclusion body Database 0.82
Category members GO Category GO:0005487 nucleocytoplasmic transporter activity Database 0.79
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0046832 negative regulation of RNA export from nucleus Database 0.34
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0046718 viral entry into host cell Database 0.04
Category members Pathway Pathway_1131 PID_SMAD2_3PATHWAY 0 0.04
Category members GO Category GO:0005215 transporter activity Database 0
Category members GO Category GO:0043495 protein anchor Database 0


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