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Query: NUP133

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NUP133 1 5.722 -2.070 3.890 0.594 0.654 0.495

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NUP133 Ubiquitylation K842 1.012 0.247 _YDNLEM(ox)EYLQK(gl)R_
NUP133 Ubiquitylation K1110 -0.210 -0.014 _LLK(gl)DGIQLSEYLPEVK_
NUP133 Ubiquitylation K1076 -0.262 _LEILCK(gl)ALQR_
NUP133 Ubiquitylation K1050 -0.275 _ANEYDFKK(gl)_
NUP133 Ubiquitylation K910 -0.319 _WYLEKGK(gl)_
NUP133 Phosphorylation S45 -1.170 _KGLPLGSAVSS(ph)PVLFS(ph)PVGR_
NUP133 Phosphorylation S50 -1.836 _KGLPLGSAVSS(ph)PVLFS(ph)PVGR_
NUP133 Ubiquitylation K1107 0.694 _ILQK(gl)LLK_

Background Information for NUP133:


Pubmed-NUP133 »
Uniprot-NUP133 »
Biogrid-NUP133 »
ProteomicsDB-NUP133 »

Tumorportal-NUP133 »
COSMIC-NUP133 »
GenomeRNAi-NUP133 »
Genecards-NUP133


Protein-protein Interactions for NUP133
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK4 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP107 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP155 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP214 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait PANK4 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEH1L Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015
Category members IP bait VIM Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEC13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPAST Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPTE2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NUP133
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Nucleoporin_Nup133/Nup155_C IPR007187 0.27
Category members Nucleoporin_Nup133/Nup155_N IPR014908 0.27


Protein complexes (CORUM database) featuring NUP133
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 87 Nup 107-160 subcomplex Database 1.16
Category members Corum 1347 NPC subcomplex (NUP98, NUP107, NUP133, NUP160) Database 1.15


Categories featuring NUP133
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members Pathway Pathway_1310 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS 0 7.24
Category members Pathway Pathway_1311 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY 0 7.24
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members Pathway Pathway_1206 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS 0 6.87
Category members GO Category GO:0005643 nuclear pore Database 6.58
Category members Pathway Pathway_878 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 0 6.53
Category members Pathway Pathway_886 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT 0 5.93
Category members GO Category GO:0010827 regulation of glucose transport Database 5.83
Category members GO Category GO:0007077 mitotic nuclear envelope disassembly Database 5.8
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_120 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN 0 5.24
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_887 REACTOME_METABOLISM_OF_NON_CODING_RNA 0 4.38
Category members GO Category GO:0008645 hexose transport Database 4.15
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_98 REACTOME_GLUCOSE_TRANSPORT 0 3.58
Category members Pathway Pathway_689 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 0 3.51
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0015758 glucose transport Database 2.09
Category members GO Category GO:0031080 nuclear pore outer ring Database 1.57
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0005487 nucleocytoplasmic transporter activity Database 0.79
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members GO Category GO:0006999 nuclear pore organization Database 0.37
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0000940 condensed chromosome outer kinetochore Database 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0048339 paraxial mesoderm development Database 0.09
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07


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