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Query: NSF

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NSF 0 -2.003 -0.060 -0.040 0.076 -1.033 0.396 0.346

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NSF Ubiquitylation K401 -1.546 -0.201 _MEIGLPDEK(gl)GR_

Background Information for NSF:


Pubmed-NSF »
Uniprot-NSF »
Biogrid-NSF »
ProteomicsDB-NSF »

Tumorportal-NSF »
COSMIC-NSF »
GenomeRNAi-NSF »
Genecards-NSF


Protein-protein Interactions for NSF
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC88A Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP6 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH6 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB4B Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIM32 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS4B Cat. description Hein, Mann, Cell 2015
Category members IP bait RBKS Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NSF
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ATPase_AAA_core IPR003959 0.14
Category members CDC48_domain_2-like IPR029067 0.12
Category members Asp_de-COase-like_dom IPR009010 0.04
Category members CDC4_N-term_subdom IPR003338 0
Category members Cdc48_dom2 IPR004201 0


Protein complexes (CORUM database) featuring NSF
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NSF
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0006887 exocytosis Database 0.2
Category members Pathway Pathway_1011 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS 0 0.18
Category members Pathway Pathway_1155 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS 0 0.13
Category members GO Category GO:0006813 potassium ion transport Database 0.11
Category members GO Category GO:0019905 syntaxin binding Database 0.05
Category members GO Category GO:0001921 positive regulation of receptor recycling Database 0.02
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_140 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 0 0
Category members Pathway Pathway_230 REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 0 0
Category members Pathway Pathway_266 KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION 0 0
Category members GO Category GO:0042623 ATPase activity, coupled Database 0
Category members GO Category GO:0045026 plasma membrane fusion Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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