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Query: NRF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NRF1 0 -0.876 -0.381 0.350 0.053

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NRF1 Phosphorylation S136 -0.407 -0.047 _VGQQAIVLCIS(ph)PSKPNPVFK_
NRF1 Ubiquitylation K267 -0.444 _TIVK(gl)NCYK_

Background Information for NRF1:


Pubmed-NRF1 »
Uniprot-NRF1 »
Biogrid-NRF1 »
ProteomicsDB-NRF1 »

Tumorportal-NRF1 »
COSMIC-NRF1 »
GenomeRNAi-NRF1 »
Genecards-NRF1


Protein-protein Interactions for NRF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait WDR59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NRF1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring NRF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NRF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0051602 response to electrical stimulus Database 0.22
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0051593 response to folic acid Database 0.01
Category members GO Category GO:0031100 organ regeneration Database 0.01
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0006091 generation of precursor metabolites and energy Database 0
Category members GO Category GO:0007005 mitochondrion organization Database 0
Category members GO Category GO:0032355 response to estradiol Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0


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