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Query: NR1D2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NR1D2 0 0.879 0.660 -0.420

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NR1D2 Ubiquitylation K467 0.879 _TVTFLSGK(gl)K_

Background Information for NR1D2:


Pubmed-NR1D2 »
Uniprot-NR1D2 »
Biogrid-NR1D2 »
ProteomicsDB-NR1D2 »

Tumorportal-NR1D2 »
COSMIC-NR1D2 »
GenomeRNAi-NR1D2 »
Genecards-NR1D2


Protein-protein Interactions for NR1D2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NR1D2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NR1D2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Nucl_hrmn_rcpt_lig-bd_core IPR000536 0
Category members Znf_hrmn_rcpt IPR001628 0
Category members Str_hrmn_rcpt IPR001723 0
Category members Nucl_hormone_rcpt_ligand-bd IPR008946 0


Protein complexes (CORUM database) featuring NR1D2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NR1D2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0030522 intracellular receptor signaling pathway Database 0.9
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members GO Category GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Database 0.03
Category members Pathway Pathway_929 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY 0 0
Category members GO Category GO:0001046 core promoter sequence-specific DNA binding Database 0
Category members GO Category GO:0003707 steroid hormone receptor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0019216 regulation of lipid metabolic process Database 0
Category members GO Category GO:0042752 regulation of circadian rhythm Database 0
Category members GO Category GO:0043401 steroid hormone mediated signaling pathway Database 0
Category members GO Category GO:0050727 regulation of inflammatory response Database 0
Category members GO Category GO:0055088 lipid homeostasis Database 0


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