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Query: NPTN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NPTN 0 1.357 0.600 -0.750 0.647 0.525

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NPTN Ubiquitylation K249 0.185 _SENK(gl)NEGQDATMYCK_
NPTN Ubiquitylation K244 -0.393 _AAPDITGHK(gl)R_

Background Information for NPTN:





Protein-protein Interactions for NPTN

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in NPTN

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members Ig_sub IPR003599 0.43
Category members Immunoglobulin IPR013151 0.23
Category members Ig_sub2 IPR003598 0.21
Category members Ig_I-set IPR013098 0.13
Category members Ig_V-set IPR013106 0.09
Category members MFS_dom_general_subst_transpt IPR016196 0


Protein complexes (CORUM database) featuring NPTN

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NPTN

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0007156 homophilic cell adhesion Database 0.28
Category members GO Category GO:0001934 positive regulation of protein phosphorylation Database 0.22
Category members GO Category GO:0010976 positive regulation of neuron projection development Database 0.05
Category members GO Category GO:0005105 type 1 fibroblast growth factor receptor binding Database 0
Category members GO Category GO:0007204 positive regulation of cytosolic calcium ion concentration Database 0
Category members GO Category GO:0042734 presynaptic membrane Database 0
Category members GO Category GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway Database 0
Category members GO Category GO:0048170 positive regulation of long-term neuronal synaptic plasticity Database 0
Category members GO Category GO:0050839 cell adhesion molecule binding Database 0
Category members GO Category GO:0060291 long-term synaptic potentiation Database 0


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