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Query: NIN

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NIN 0 0.725 0.060 -0.430
NIN 0 0.725 0.060 -0.430 0.464 -0.153

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NIN Phosphorylation S1783 0.414 _VQNLEDTVQNVNLQM(ox)S(ph)R_

Background Information for NIN:


Pubmed-NIN »
Uniprot-NIN »
Biogrid-NIN »
ProteomicsDB-NIN »

Tumorportal-NIN »
COSMIC-NIN »
GenomeRNAi-NIN »
Genecards-NIN


Protein-protein Interactions for NIN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AZI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BAX Cat. description Hein, Mann, Cell 2015
Category members IP bait DOT1L Cat. description Hein, Mann, Cell 2015
Category members IP bait FUS Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH13 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR61 Cat. description Hein, Mann, Cell 2015
Category members IP bait C17orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C22orf41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CASQ2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC68 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CEP170 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCP10L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF331 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NIN
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members tRNA-bd_arm IPR010978 0.08
Category members EF_hand_dom IPR002048 0


Protein complexes (CORUM database) featuring NIN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NIN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0005814 centriole Database 0
Category members GO Category GO:0034454 microtubule anchoring at centrosome Database 0
Category members GO Category GO:0051642 centrosome localization Database 0


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