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Query: NHP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NHP2 0 -1.860 1.460 -0.060 -0.832 -0.790 -0.238

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for NHP2:





Protein-protein Interactions for NHP2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GAR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCHE Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NHP2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members H/ACA_rnp_Nhp2_euk IPR002415 0
Category members Ribosomal_L7Ae/L30e/S12e/Gad45 IPR004038 0
Category members Ribosomal_L7Ae/L8/Nhp2 IPR018492 0
Category members L30e-like IPR029064 0


Protein complexes (CORUM database) featuring NHP2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NHP2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_328 REACTOME_TELOMERE_MAINTENANCE 0 3.74
Category members Pathway Pathway_324 REACTOME_EXTENSION_OF_TELOMERES 0 0.33
Category members GO Category GO:0030515 snoRNA binding Database 0.07
Category members GO Category GO:0015030 Cajal body Database 0.04
Category members Disease phenotype Dyskeratosis_congenita Dyskeratosis congenita Database 0
Category members GO Category GO:0005732 small nucleolar ribonucleoprotein complex Database 0


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