bioLOGIC-db

bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

Query: NEXN

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
W

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
NEXN	0	1.315	0.410	-0.530

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
NEXN	Phosphorylation	S365	0.094	0.720	_TIS(ph)QEFLTPGK_
NEXN	Phosphorylation	S80	0.595	0.611	_EM(ox)LAS(ph)DDEEDVSSK_

Background Information for NEXN:

Pubmed-NEXN »

Uniprot-NEXN »

Biogrid-NEXN »

ProteomicsDB-NEXN »

Tumorportal-NEXN »

COSMIC-NEXN »

GenomeRNAi-NEXN »

Genecards-NEXN

Protein-protein Interactions for NEXN

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait ACTB	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait ANLN	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CALML3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CAPZA2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CORO1C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait DBN1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait FLNA	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait FLNB	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait FLOT1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait FLOT2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait IQGAP1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait LIMA1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MAPRE1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYH10	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYH9	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYO18A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYO19	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYO1C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYO5C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PPP1CB	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SYNPO	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TMOD3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TPM1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TPX2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait NEXN	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in NEXN

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Ig-like_dom	IPR007110	0.6
Category members	Ig_sub	IPR003599	0.43
Category members	Ig_I-set	IPR013098	0.13

Protein complexes (CORUM database) featuring NEXN

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring NEXN

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0051015	actin filament binding	Database	0.99
Category members	GO Category	GO:0005856	cytoskeleton	Database	0.63
Category members	GO Category	GO:0030334	regulation of cell migration	Database	0.61
Category members	GO Category	GO:0030018	Z disc	Database	0.32
Category members	Disease phenotype	Familial_isolated_dilated_cardiomyopathy	Familial isolated dilated cardiomyopathy	Database	0.08
Category members	GO Category	GO:0051493	regulation of cytoskeleton organization	Database	0.04
Category members	GO Category	GO:0005924	cell-substrate adherens junction	Database	0
Category members	GO Category	GO:0008307	structural constituent of muscle	Database	0