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Query: NEK9

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NEK9 0 3.049 1.890 -1.000

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NEK9 Ubiquitylation K366 0.951 0.744 _LDVIK(gl)SGCSAR_
NEK9 Phosphorylation T333 0.736 0.618 _SST(ph)VTEAPIAVVTSR_
NEK9 Phosphorylation S331 0.416 0.370 _S(ph)STVTEAPIAVVTSR_
NEK9 Phosphorylation S869 -0.369 0.355 _VASEAPLEHKPQVEAS(ph)SPR_
NEK9 Phosphorylation S868 -0.169 -0.040 _VASEAPLEHKPQVEAS(ph)SPR_
NEK9 Ubiquitylation K200 -0.124 _LGDYGLAKK(gl)_
NEK9 Ubiquitylation K606 -0.077 -0.476 _TIAPGK(gl)THTAAIDER_
NEK9 Phosphorylation S332 -0.579 _SS(ph)TVTEAPIAVVTSR_
NEK9 Ubiquitylation K327 -1.575 _VTLLNAPTK(gl)RPR_
NEK9 Ubiquitylation K361 -1.833 _STPQK(gl)LDVIK_

Background Information for NEK9:





Protein-protein Interactions for NEK9

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BAG3 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEK9 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRAPPC8 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MAFF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEK6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NEK9

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RCC1/BLIP-II IPR009091 0.24
Category members Reg_chr_condens IPR000408 0.23
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring NEK9

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 934 FACT-NEK9 complex Database 0.79


Categories featuring NEK9

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0007077 mitotic nuclear envelope disassembly Database 5.8
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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