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Query: NEFM

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NEFM 0 2.275 0.610 -0.040 0.848 0.710 0.717

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for NEFM:





Protein-protein Interactions for NEFM

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NEFM Cat. description Hein, Mann, Cell 2015
Category members IP bait C9orf150 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC106 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC120 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM167A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKBKG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLLT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEFH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSPRY1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYNC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIM Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NEFM

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Intermed_filament_DNA-bd IPR006821 0.07
Category members Keratin_I IPR002957 0
Category members IF IPR001664 0
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring NEFM

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NEFM

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members Pathway Pathway_420 KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS 0 0.39
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0005883 neurofilament Database 0.06
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0005882 intermediate filament Database 0
Category members GO Category GO:0008088 axon cargo transport Database 0
Category members GO Category GO:0031133 regulation of axon diameter Database 0
Category members GO Category GO:0031594 neuromuscular junction Database 0
Category members GO Category GO:0045104 intermediate filament cytoskeleton organization Database 0
Category members GO Category GO:0045110 intermediate filament bundle assembly Database 0
Category members GO Category GO:0060052 neurofilament cytoskeleton organization Database 0


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