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Query: NAMPT

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NAMPT 0 -1.484 -0.050 -0.460 0.270 -2.796

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NAMPT Ubiquitylation K228 1.042 _GTDTVAGLALIK(gl)K_
NAMPT Ubiquitylation K330 -0.016 _VLEILGK(gl)K_

Background Information for NAMPT:


Pubmed-NAMPT »
Uniprot-NAMPT »
Biogrid-NAMPT »
ProteomicsDB-NAMPT »

Tumorportal-NAMPT »
COSMIC-NAMPT »
GenomeRNAi-NAMPT »
Genecards-NAMPT


Protein-protein Interactions for NAMPT
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C16orf71 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NAMPT
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Quinolinate_PRibosylTrfase_C IPR002638 0


Protein complexes (CORUM database) featuring NAMPT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NAMPT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005125 cytokine activity Database 1.06
Category members GO Category GO:0007267 cell-cell signaling Database 0.94
Category members Pathway Pathway_157 REACTOME_CIRCADIAN_CLOCK 0 0.92
Category members Pathway Pathway_748 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION 0 0.66
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006767 water-soluble vitamin metabolic process Database 0.27
Category members GO Category GO:0006766 vitamin metabolic process Database 0.23
Category members Pathway Pathway_279 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS 0 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process Database 0.01
Category members Pathway Pathway_281 KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM 0 0
Category members GO Category GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0009435 NAD biosynthetic process Database 0
Category members GO Category GO:0019674 NAD metabolic process Database 0


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