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Query: MYO1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MYO1A 0 4.672 -0.730 0.450 0.137 0.249 1.311 0.007

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MYO1A Ubiquitylation K354 1.472 _DALAK(gl)NLYSR_
MYO1A Ubiquitylation K588 -0.892 _NLQTK(gl)NPNYIR_
MYO1A Ubiquitylation K303 -0.725 _IKDK(gl)NELK_
MYO1A Ubiquitylation K972 0.034 _ALYPSSVGQPFQGAYLEINK(gl)NPK_
MYO1A Ubiquitylation K980 1.046 _LK(gl)DAIEEK_

Background Information for MYO1A:





Protein-protein Interactions for MYO1A

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIF1C Cat. description Hein, Mann, Cell 2015


Protein Domains in MYO1A

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Myosin_head_motor_dom IPR001609 0.17
Category members IQ_motif_EF-hand-BS IPR000048 0
Category members Myosin_tail_2 IPR010926 0


Protein complexes (CORUM database) featuring MYO1A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MYO1A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0016328 lateral plasma membrane Database 0.41
Category members GO Category GO:0016459 myosin complex Database 0.38
Category members GO Category GO:0030033 microvillus assembly Database 0.23
Category members GO Category GO:0003774 motor activity Database 0.2
Category members GO Category GO:0005902 microvillus Database 0.13
Category members GO Category GO:0030864 cortical actin cytoskeleton Database 0.06
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members GO Category GO:0031941 filamentous actin Database 0.01
Category members Disease phenotype Autosomal_dominant_nonsyndromic_sensorineural_deafness_type_DFNA Autosomal dominant nonsyndromic sensorineural deafness type DFNA Database 0
Category members GO Category GO:0005903 brush border Database 0
Category members GO Category GO:0007605 sensory perception of sound Database 0
Category members GO Category GO:0009925 basal plasma membrane Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0030030 cell projection organization Database 0
Category members GO Category GO:0051648 vesicle localization Database 0


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