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Query: MYBL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MYBL2 2 7.181 -1.160 2.880

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MYBL2 Phosphorylation S421 3.255 _VALS(ph)PVTENSTSLSFLDSCNSLTPK_
MYBL2 Phosphorylation S241 1.046 0.481 _EEENS(ph)EEELAAATTSK_
MYBL2 Phosphorylation S393 0.881 0.234 _GELIPIS(ph)PSTEVGGSGIGTPPSVLK_
MYBL2 Phosphorylation T266 -0.189 -0.901 _EQEPIGTDLDAVRT(ph)PEPLEEFPK_
MYBL2 Phosphorylation S452 -0.134 -1.114 _TLPFS(ph)PSQFLNFWNK_

Background Information for MYBL2:





Protein-protein Interactions for MYBL2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C14ORF10;PPP2R3C Cat. description Hein, Mann, Cell 2015
Category members IP bait CTDSPL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PANK4 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF187 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIN37 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIN9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MYBL2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SANT/Myb IPR001005 2.18
Category members Myb-like_dom IPR017877 0.63
Category members Homeodomain-like IPR009057 0
Category members C-myb_C IPR015395 0


Protein complexes (CORUM database) featuring MYBL2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5589 LINC complex, S-phase Database 0.01
Category members Corum 839 LIN9-BMYB complex Database 0


Categories featuring MYBL2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_313 REACTOME_MITOTIC_G1_G1_S_PHASES 0 1.45
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members Pathway Pathway_325 PID_E2F_PATHWAY 0 0.62
Category members GO Category GO:0031523 Myb complex Database 0.05
Category members Pathway Pathway_869 REACTOME_G0_AND_EARLY_G1 0 0


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