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Query: MTA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTA1 1 3.779 0.420 -0.750 0.270 0.038 0.594 0.680 0.342

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MTA1 Phosphorylation S449 0.341 0.243 _SNMS(ph)PHGLPAR_
MTA1 Phosphorylation S522 0.104 0.178 _LPEASQS(ph)PLVLK_
MTA1 Ubiquitylation K527 -0.182 -0.384 _LPEASQSPLVLK(gl)QAVR_
MTA1 Ubiquitylation K352 -0.839 _AAEAESKLK(gl)_
MTA1 Ubiquitylation K164 -1.108 _TLLADK(gl)GEIR_
MTA1 Phosphorylation S576 -1.765 -1.404 _VAPVINNGS(ph)PTILGK_
MTA1 Phosphorylation T564 -0.749 -1.930 _SVSSVLSSLT(ph)PAK_
MTA1 Ubiquitylation K340 1.655 _TTDRYVQQK(gl)R_
MTA1 Phosphorylation S446 -0.199 _S(ph)NM(ox)SPHGLPAR_
MTA1 Ubiquitylation K462 -0.047 _SSGSPK(gl)FAMK_
MTA1 Phosphorylation S520 -0.126 _LPEAS(ph)QSPLVLK_

Background Information for MTA1:


Pubmed-MTA1 »
Uniprot-MTA1 »
Biogrid-MTA1 »
ProteomicsDB-MTA1 »

Tumorportal-MTA1 »
COSMIC-MTA1 »
GenomeRNAi-MTA1 »
Genecards-MTA1


Protein-protein Interactions for MTA1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR1B Cat. description Hein, Mann, Cell 2015
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait BSDC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2AP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait MBD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait TIGD6 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS1BP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VIM Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS18 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZMYND8 Cat. description Hein, Mann, Cell 2015
Category members IP bait C9orf25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPNE5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATAD2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATAD2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait L3MBTL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBD3L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHF20L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF219 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MTA1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SANT/Myb IPR001005 2.18
Category members BAH_dom IPR001025 0.62
Category members ELM2_dom IPR000949 0.51
Category members Znf_GATA IPR000679 0.29
Category members Homeodomain-like IPR009057 0


Protein complexes (CORUM database) featuring MTA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 282 SNF2h-cohesin-NuRD complex Database 6.11
Category members Corum 614 NRD complex (Nucleosome remodeling and deacetylation complex) Database 2.26
Category members Corum 632 Anti-HDAC2 complex Database 2.11
Category members Corum 886 MTA1 complex Database 1.68
Category members Corum 889 MTA1-HDAC core complex Database 1.41
Category members Corum 2657 ESR1-CDK7-CCNH-MNAT1-MTA1-HDAC2 complex Database 0.15


Categories featuring MTA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016581 NuRD complex Database 1.15
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members Pathway Pathway_185 PID_ERA_GENOMIC_PATHWAY 0 1.05
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members Pathway Pathway_54 BIOCARTA_MTA3_PATHWAY 0 0.36
Category members GO Category GO:0001103 RNA polymerase II repressing transcription factor binding Database 0.36
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0033363 secretory granule organization Database 0.02
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007165 signal transduction Database 0


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