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Query: MRPL3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MRPL3 0 -0.975 0.860 -0.570 -0.326 0.403 0.086 -0.641 -0.026

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MRPL3 Ubiquitylation K247 -0.471 _GFQGVMK(gl)R_
MRPL3 Ubiquitylation K335 -0.997 _LPAYK(gl)DLGK_
MRPL3 Ubiquitylation K177 -1.018 _MATLSVGGK(gl)TVSR_

Background Information for MRPL3:


Pubmed-MRPL3 »
Uniprot-MRPL3 »
Biogrid-MRPL3 »
ProteomicsDB-MRPL3 »

Tumorportal-MRPL3 »
COSMIC-MRPL3 »
GenomeRNAi-MRPL3 »
Genecards-MRPL3


Protein-protein Interactions for MRPL3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BACH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC12 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPA Cat. description Hein, Mann, Cell 2015
Category members IP bait GBF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GPSM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MRPL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MRPL50 Cat. description Hein, Mann, Cell 2015
Category members IP bait MRPL9 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NFYA Cat. description Hein, Mann, Cell 2015
Category members IP bait SCAF11 Cat. description Hein, Mann, Cell 2015
Category members IP bait TIMM13 Cat. description Hein, Mann, Cell 2015
Category members IP bait TOPBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS28 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL35 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL39 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL42 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPAN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MRPL3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Transl_B-barrel IPR009000 0.24
Category members Ribosomal_L3 IPR000597 0.14


Protein complexes (CORUM database) featuring MRPL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 320 55S ribosome, mitochondrial Database 0.3
Category members Corum 324 39S ribosomal subunit, mitochondrial Database 0.08


Categories featuring MRPL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0003735 structural constituent of ribosome Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0005840 ribosome Database 12.2
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0005762 mitochondrial large ribosomal subunit Database 0.07


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