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Query: MPP6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MPP6 0 3.658 0.130 0.100 1.137 0.965 0.797

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MPP6 Ubiquitylation K242 0.219 _EAGLK(gl)FSK_
MPP6 Ubiquitylation K403 0.759 _AGK(gl)YLEHGEYEGNLYGTK_

Background Information for MPP6:





Protein-protein Interactions for MPP6

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LIN7C Cat. description Hein, Mann, Cell 2015
Category members IP bait MPP6 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP2S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DMD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM188A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIN7C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAT9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSUN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC20A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MPP6

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members L27 IPR004172 1.84
Category members GK/Ca_channel_bsu IPR008145 1.36
Category members Guanylate_kin-like IPR008144 1.32
Category members L27_C IPR014775 0.33
Category members PDZ IPR001478 0.15
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring MPP6

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1089 VAM1-VELI1 complex Database 0


Categories featuring MPP6

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0030165 PDZ domain binding Database 0.29


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