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Query: MPP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MPP2 0 2.398 0.810 -0.250
MPP2 0 2.398 0.810 -0.250 0.384 1.226

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MPP2 Phosphorylation S59 -0.018 0.387 _GIMES(ph)PIVR_
MPP2 Phosphorylation T131 -0.991 _T(ph)YETPPPSPGLDPTFSNQPVPPDAVR_
MPP2 Phosphorylation T134 -0.839 -1.499 _TYET(ph)PPPS(ph)PGLDPTFSNQPVPPDAVR_
MPP2 Phosphorylation S138 -1.041 -1.640 _TYET(ph)PPPS(ph)PGLDPTFSNQPVPPDAVR_
MPP2 Ubiquitylation K583 0.419 _ELQTAMEK(gl)LR_

Background Information for MPP2:





Protein-protein Interactions for MPP2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP2S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISOC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC20A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MPP2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members L27 IPR004172 1.84
Category members GK/Ca_channel_bsu IPR008145 1.36
Category members Guanylate_kin-like IPR008144 1.32
Category members L27_C IPR014775 0.33
Category members PDZ IPR001478 0.15
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring MPP2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MPP2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0004385 guanylate kinase activity Database 1.77
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members GO Category GO:0007165 signal transduction Database 0


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