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Query: MMS19

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MMS19 0 -0.344 0.790 -0.240 0.022 0.032

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MMS19 Ubiquitylation K517 -0.398 _LSFLK(gl)EDSQSCR_
MMS19 Ubiquitylation K394 -1.127 _LVWPSAK(gl)_

Background Information for MMS19:





Protein-protein Interactions for MMS19

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP7A Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait ESPL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MMS19 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCSTN Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait DNA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MMS19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPPED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MMS19

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring MMS19

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MMS19

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006289 nucleotide-excision repair Database 6.65
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005675 holo TFIIH complex Database 0.83
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0030674 protein binding, bridging Database 0.25
Category members GO Category GO:0000160 phosphorelay signal transduction system Database 0.19
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members GO Category GO:0009725 response to hormone Database 0.01
Category members GO Category GO:0006259 DNA metabolic process Database 0
Category members GO Category GO:0016226 iron-sulfur cluster assembly Database 0
Category members GO Category GO:0030159 receptor signaling complex scaffold activity Database 0
Category members GO Category GO:0030331 estrogen receptor binding Database 0


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