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Query: MLLT3

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MLLT3 0 1.065 0.980 -0.760

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MLLT3 Phosphorylation S522 0.537 0.528 _TNNNQILEVKS(ph)PIK_

Background Information for MLLT3:


Pubmed-MLLT3 »
Uniprot-MLLT3 »
Biogrid-MLLT3 »
ProteomicsDB-MLLT3 »

Tumorportal-MLLT3 »
COSMIC-MLLT3 »
GenomeRNAi-MLLT3 »
Genecards-MLLT3


Protein-protein Interactions for MLLT3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AFF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DOT1L Cat. description Hein, Mann, Cell 2015
Category members IP bait ELL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLLT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C20orf114 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DENND2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EAF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOSC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM9A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MDK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLLT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PES1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MLLT3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members YEATS IPR005033 0


Protein complexes (CORUM database) featuring MLLT3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MLLT3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007379 segment specification Database 0


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