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Query: MLEC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MLEC 0 0.527 0.390 0.137

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for MLEC:


Pubmed-MLEC »
Uniprot-MLEC »
Biogrid-MLEC »
ProteomicsDB-MLEC »

Tumorportal-MLEC »
COSMIC-MLEC »
GenomeRNAi-MLEC »
Genecards-MLEC


Protein-protein Interactions for MLEC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait TSNAX Cat. description Hein, Mann, Cell 2015
Category members IP bait RPN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MLEC
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring MLEC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MLEC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members Pathway Pathway_464 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE 0 0
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0030246 carbohydrate binding Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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