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Query: METAP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
METAP2 1 -1.485 0.200 -0.960 -1.520 -1.105

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
METAP2 Ubiquitylation K427 -0.662 1.802 _LGESK(gl)YLMALK_
METAP2 Ubiquitylation K323 0.948 _TYQVK(gl)PIR_
METAP2 Ubiquitylation K289 -0.679 0.423 _DATNTGIK(gl)CAGIDVR_
METAP2 Ubiquitylation K281 -0.346 _AVK(gl)DATNTGIK_

Background Information for METAP2:


Pubmed-METAP2 »
Uniprot-METAP2 »
Biogrid-METAP2 »
ProteomicsDB-METAP2 »

Tumorportal-METAP2 »
COSMIC-METAP2 »
GenomeRNAi-METAP2 »
Genecards-METAP2


Protein-protein Interactions for METAP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FGFR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ASB6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1QB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCT7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CUL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DLK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FCRL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNAS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPBP1L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRIA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LILRB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL35 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLIN5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PVR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RGS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUCLA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM108 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM194A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM213 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in METAP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Pept_M24_MAP IPR001714 0.04
Category members Pept_M24_structural-domain IPR000994 0


Protein complexes (CORUM database) featuring METAP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring METAP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016485 protein processing Database 0.57
Category members GO Category GO:0008235 metalloexopeptidase activity Database 0.33
Category members GO Category GO:0018206 peptidyl-methionine modification Database 0.3
Category members GO Category GO:0007603 phototransduction, visible light Database 0.25
Category members GO Category GO:0004177 aminopeptidase activity Database 0.13
Category members GO Category GO:0031365 N-terminal protein amino acid modification Database 0.13
Category members GO Category GO:0016056 rhodopsin mediated signaling pathway Database 0.04
Category members GO Category GO:0022400 regulation of rhodopsin mediated signaling pathway Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0070006 metalloaminopeptidase activity Database 0


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