bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: MED12L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MED12L 0 -4.343 0.560 -0.390 -1.501 -0.491

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MED12L Ubiquitylation K531 -0.272 _AMVVAKLLEK(gl)_
MED12L Ubiquitylation K429 -0.439 _EIEQQIK(gl)ER_
MED12L Ubiquitylation K1682 -0.745 _EGLQVSTK(gl)QK_
MED12L Phosphorylation S635 -1.278 -0.801 _GDLAFGAPGPRPPS(ph)PFDDPADDPEHK_
MED12L Ubiquitylation K1684 -0.960 _EGLQVSTK(gl)QK_
MED12L Ubiquitylation K1001 -1.092 _VK(gl)NTIYCNVEPSESNMR_
MED12L Ubiquitylation K1661 -1.781 _DVITCEPQGSLIDTK(gl)GNK_

Background Information for MED12L:


Pubmed-MED12L »
Uniprot-MED12L »
Biogrid-MED12L »
ProteomicsDB-MED12L »

Tumorportal-MED12L »
COSMIC-MED12L »
GenomeRNAi-MED12L »
Genecards-MED12L


Protein-protein Interactions for MED12L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCNC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MED12L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Mediator_Med12 IPR019035 0
Category members Mediator_Med12_catenin-bd IPR021989 0
Category members Mediator_Med12_LCEWAV IPR021990 0


Protein complexes (CORUM database) featuring MED12L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MED12L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016592 mediator complex Database 0.53
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0008013 beta-catenin binding Database 0.35
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0001104 RNA polymerase II transcription cofactor activity Database 0.08


.

© Copyright Svejstrup Laboratory 2015