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Query: MDN1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MDN1 0 2.444 0.760 -0.410 -0.386 0.101 0.229 0.029 0.186

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MDN1 Phosphorylation S4538 0.436 0.524 _AEENTDQAS(ph)PQEDYAGFER_
MDN1 Ubiquitylation K366 0.195 _VQLGDQTDSK(gl)MLLGMYR_
MDN1 Ubiquitylation K33 -0.035 _FLAK(gl)QVWTPQDR_
MDN1 Ubiquitylation K19 -0.287 _LIAAK(gl)NEK_
MDN1 Ubiquitylation K3545 0.744 -0.412 _IAQEK(gl)AEQESGLYR_
MDN1 Ubiquitylation K2471 -0.474 _MSMK(gl)TSSWTR_
MDN1 Phosphorylation T4898 -0.733 _VPEPEALDLPDDLNLDSEDKNGGEDT(ph)DNEEGEEENPLEIK_
MDN1 Ubiquitylation K891 -0.938 _LFACMNPATDVGK(gl)R_
MDN1 Ubiquitylation K3313 -1.031 _LDNLTCHLLKK(gl)_
MDN1 Ubiquitylation K1863 -1.113 _TK(gl)IFGCQNPFR_
MDN1 Ubiquitylation K350 -1.164 _TK(gl)PPQLLK_
MDN1 Ubiquitylation K600 -1.233 _MAEVIGSK(gl)LNISR_
MDN1 Phosphorylation S5015 0.186 -1.308 _DKEADEEGGENGPADQGFQPQEEEEREDS(ph)DTEEQVPEALER_
MDN1 Ubiquitylation K1529 -1.319 _ILATMNPGGDFGK(gl)K_
MDN1 Ubiquitylation K1530 -1.319 _ILATMNPGGDFGK(gl)K_
MDN1 Ubiquitylation K1514 -1.438 _GSPEDKDSEIELLTAGKK(gl)_
MDN1 Ubiquitylation K1024 -2.534 _SLLK(gl)QPIPEPK_
MDN1 Ubiquitylation K1746 0.030 _LK(gl)KPILLEGSPGVGK_
MDN1 Ubiquitylation K1747 0.030 _LK(gl)KPILLEGSPGVGK_
MDN1 Phosphorylation T5017 0.186 _DKEADEEGGENGPADQGFQPQEEEEREDS(ph)DTEEQVPEALER_

Background Information for MDN1:





Protein-protein Interactions for MDN1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BECN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait GSK3A Cat. description Hein, Mann, Cell 2015
Category members IP bait STK17B Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015
Category members IP bait WIZ Cat. description Hein, Mann, Cell 2015
Category members IP bait APLNR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPEP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PARP16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGOLN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MDN1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members P-loop_NTPase IPR027417 2.83
Category members ATPase_dyneun-rel_AAA IPR011704 2.54
Category members ATPase_AAA-3 IPR011703 0.65
Category members AAA+_ATPase IPR003593 0.38
Category members VWF_A IPR002035 0


Protein complexes (CORUM database) featuring MDN1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MDN1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0006200 ATP catabolic process Database 2.13
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5


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