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Query: MCRS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MCRS1 0 1.298 -1.000 0.700

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MCRS1 Phosphorylation S22 0.474 0.424 _(ac)ASGTASRS(ph)EDEESLAGQK_
MCRS1 Phosphorylation S282 0.297 0.169 _GDQVLNFS(ph)DAEDLIDDSK_
MCRS1 Ubiquitylation K211 -0.300 _ALFSK(gl)AEEQLLSK_

Background Information for MCRS1:





Protein-protein Interactions for MCRS1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait COPS7A Cat. description Hein, Mann, Cell 2015
Category members IP bait KAT8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPBP1L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INTU Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1267 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NECAB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHF20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UCHL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MCRS1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FHA_dom IPR000253 2.3
Category members SMAD_FHA_domain IPR008984 0.86


Protein complexes (CORUM database) featuring MCRS1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5386 MLL1-WDR5 complex Database 0.31
Category members Corum 302 INO80 chromatin remodeling complex Database 0.14
Category members Corum 1057 DIPA-MCRS1 complex Database 0


Categories featuring MCRS1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0071339 MLL1 complex Database 0.45
Category members GO Category GO:0043981 histone H4-K5 acetylation Database 0.43
Category members GO Category GO:0043982 histone H4-K8 acetylation Database 0.43
Category members GO Category GO:0031011 Ino80 complex Database 0.29
Category members GO Category GO:0000123 histone acetyltransferase complex Database 0.15
Category members GO Category GO:0043984 histone H4-K16 acetylation Database 0.07
Category members GO Category GO:0043995 histone acetyltransferase activity (H4-K5 specific) Database 0.04
Category members GO Category GO:0043996 histone acetyltransferase activity (H4-K8 specific) Database 0.04
Category members GO Category GO:0046972 histone acetyltransferase activity (H4-K16 specific) Database 0.04
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006464 cellular protein modification process Database 0


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