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Query: MCCC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MCCC1 0 -0.551 0.410 -0.310 -0.873 0.094 0.228

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for MCCC1:


Pubmed-MCCC1 »
Uniprot-MCCC1 »
Biogrid-MCCC1 »
ProteomicsDB-MCCC1 »

Tumorportal-MCCC1 »
COSMIC-MCCC1 »
GenomeRNAi-MCCC1 »
Genecards-MCCC1


Protein-protein Interactions for MCCC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACSM5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ECH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FECH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXRED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GCAT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait METTL2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OXCT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUCLA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUFM Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MCCC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CbamoylP_synth_lsu-like_ATP-bd IPR005479 0.91
Category members Biotin_COase_C IPR005482 0.66
Category members Rudment_hybrid_motif IPR011054 0.66
Category members Biotin_carboxylation_dom IPR011764 0.66
Category members PreATP-grasp_dom IPR016185 0.62
Category members CarbamoylP_synth_lsu_N IPR005481 0.58
Category members ATP-grasp IPR011761 0.35
Category members ATP-grasp_carboxylate-amine IPR003135 0.3
Category members Dala_Dala_lig_C IPR011095 0.3
Category members ATP-grasp_RimK-type IPR013651 0.21
Category members Biotin_lipoyl IPR000089 0.04
Category members Single_hybrid_motif IPR011053 0.02
Category members ATP-grasp_DUF201-type IPR003806 0


Protein complexes (CORUM database) featuring MCCC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MCCC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0009374 biotin binding Database 0.3
Category members GO Category GO:0006767 water-soluble vitamin metabolic process Database 0.27
Category members GO Category GO:0006766 vitamin metabolic process Database 0.23
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0004075 biotin carboxylase activity Database 0.13
Category members GO Category GO:0008716 D-alanine-D-alanine ligase activity Database 0.13
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_19 KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION 0 0.04
Category members GO Category GO:0006768 biotin metabolic process Database 0.02
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members Pathway Pathway_18 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM 0 0
Category members GO Category GO:0004485 methylcrotonoyl-CoA carboxylase activity Database 0
Category members GO Category GO:0006552 leucine catabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0009083 branched-chain amino acid catabolic process Database 0
Category members GO Category GO:0016874 ligase activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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