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Query: MARK3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MARK3 1 4.953 -0.380 -0.380
MARK3 1 4.953 -0.380 -0.380 -1.027 -0.513

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MARK3 Phosphorylation S601 3.150 1.434 _SRGS(ph)TNLFSK_
MARK3 Ubiquitylation K611 1.472 0.816 _LTSK(gl)LTR_
MARK3 Ubiquitylation K60 0.583 _LLK(gl)TIGK_
MARK3 Phosphorylation S598 0.204 -0.252 _S(ph)RGSTNLFSK_
MARK3 Phosphorylation S152 -0.326 _SSEVRPSSDLNNSTGQS(ph)PHHK_
MARK3 Phosphorylation Y418 -0.710 _RY(ph)SDHAGPAIPSVVAYPK_
MARK3 Ubiquitylation K294 -0.769 -0.738 _FLVLNPIK(gl)R_
MARK3 Phosphorylation S419 -0.429 -0.896 _RYS(ph)DHAGPAIPSVVAYPK_
MARK3 Phosphorylation S469 -1.030 -1.041 _GIAPAS(ph)PMLGNASNPNK_
MARK3 Phosphorylation S400 -1.394 _VRPSSDLNNSTGQS(ph)PHHK_
MARK3 Ubiquitylation K303 -1.652 _GTLEQIMK(gl)DR_

Background Information for MARK3:


Pubmed-MARK3 »
Uniprot-MARK3 »
Biogrid-MARK3 »
ProteomicsDB-MARK3 »

Tumorportal-MARK3 »
COSMIC-MARK3 »
GenomeRNAi-MARK3 »
Genecards-MARK3


Protein-protein Interactions for MARK3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCL7C Cat. description Hein, Mann, Cell 2015
Category members IP bait CPSF3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DLG5 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CB Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAZ Cat. description Hein, Mann, Cell 2015
Category members IP bait CASQ2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COL4A3BP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MANSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUAK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMCC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MARK3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBA-like IPR009060 0.17
Category members UBA/transl_elong_EF1B_N_euk IPR015940 0.04
Category members Kinase-like_dom IPR011009 0.03
Category members KA1/Ssp2_C IPR028375 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members KA1_dom IPR001772 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring MARK3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MARK3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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