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Query: MARCKS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MARCKS 1 3.198 -0.714 -0.493

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MARCKS Phosphorylation T120 2.170 _EAPAEGEAAEPGSPT(ph)AAEGEAASAASSTSSPK_
MARCKS Phosphorylation S170 0.673 0.812 _LSGFS(ph)FKK_
MARCKS Phosphorylation S118 1.269 0.731 _EAPAEGEAAEPGS(ph)PTAAEGEAASAASST(ph)SSPK_
MARCKS Ubiquitylation K173 0.527 0.439 _LSGFSFKK(gl)_
MARCKS Phosphorylation S46 0.247 0.291 _VNGDAS(ph)PAAAESGAK_
MARCKS Phosphorylation S167 0.189 0.018 _SFKLS(ph)GFSFK_
MARCKS Phosphorylation S147 -1.153 -0.055 _AEDGATPSPS(ph)NETPK_
MARCKS Phosphorylation S101 -0.221 -0.156 _GEPAAAAAPEAGAS(ph)PVEK_
MARCKS Phosphorylation S29 -0.564 -0.205 _GEAAAERPGEAAVASSPS(ph)K_
MARCKS Phosphorylation S26 -0.259 -0.322 _GEAAAERPGEAAVAS(ph)SPSK_
MARCKS Phosphorylation S27 -0.250 -0.326 _GEAAAERPGEAAVASS(ph)PSK_
MARCKS Phosphorylation S163 -0.398 _S(ph)FKLS(ph)GFSFK_
MARCKS Phosphorylation S145 -0.490 -0.454 _AEDGATPS(ph)PSNETPK_
MARCKS Phosphorylation T150 -0.914 -0.554 _AEDGAT(ph)PSPSNET(ph)PK_
MARCKS Phosphorylation T143 -1.973 -1.525 _AEDGAT(ph)PSPSNET(ph)PK_
MARCKS Ubiquitylation K11 -0.398 _TAAK(gl)GEAAAERPGEAAVASSPSK_

Background Information for MARCKS:





Protein-protein Interactions for MARCKS

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in MARCKS

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring MARCKS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MARCKS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006112 energy reserve metabolic process Database 0.21
Category members Pathway Pathway_681 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE 0 0.13
Category members Pathway Pathway_698 BIOCARTA_CALCINEURIN_PATHWAY 0 0.11
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members Pathway Pathway_270 REACTOME_REGULATION_OF_INSULIN_SECRETION 0 0.09
Category members GO Category GO:0050796 regulation of insulin secretion Database 0.06
Category members GO Category GO:0005080 protein kinase C binding Database 0.04
Category members GO Category GO:0042585 germinal vesicle Database 0


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