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REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE
(Pathway_681)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
GNA11 1 2.030 -1.240 0.953 0.764 0.108
PRKCA 0 0.750 -0.690 0.349 0.585
PRKCA 0 0.750 -0.690
GNA14 0 1.610 -0.450 0.492
GNAQ 0 0.140 -0.310 0.052 0.449
PLCB1 0 -0.300 -0.220

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
GNA11 Ubiquitylation K16 0.347 _(ac)TLESMMACCLSDEVK(gl)ESKR_
GNA11 Ubiquitylation K27 0.292 1.135 _RINAEIEK(gl)QLR_
GNA11 Ubiquitylation K102 0.502 0.512 _ILYK(gl)YEQNK_
GNAQ Ubiquitylation K16 0.245 _TLESIMACCLSEEAK(gl)EAR_
GNAQ Ubiquitylation K102 -0.299 _IPYK(gl)YEHNK_
PLCB1 Phosphorylation S1199 -0.494 _TPS(ph)SEELGGDIPGKEFDTPL_
PLCB1 Phosphorylation S1200 -0.483 _TPSS(ph)EELGGDIPGKEFDTPL_
PRKCA Phosphorylation S10 -0.650 0.036 _(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA Phosphorylation S13 -1.038 0.335 _(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA Phosphorylation S226 0.693 0.415 _STLNPQWNES(ph)FTFK_
PRKCA Ubiquitylation K316 -0.522 -0.535 _LGPAGNK(gl)VISPSEDR_


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