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Query: MAPRE1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAPRE1 0 -2.002 1.670 -1.110 -0.525 -0.434 -0.532

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAPRE1 Ubiquitylation K220 0.230 0.891 _DFYFGK(gl)LR_
MAPRE1 Phosphorylation S155 -0.696 _KPLTS(ph)SSAAPQRPISTQR_
MAPRE1 Phosphorylation T166 -1.133 -0.732 _KPLTSSSAAPQRPIST(ph)QR_
MAPRE1 Ubiquitylation K83 0.426 _ILQAGFK(gl)R_
MAPRE1 Ubiquitylation K148 -1.162 _QGQETAVAPSLVAPALNK(gl)PK_

Background Information for MAPRE1:


Pubmed-MAPRE1 »
Uniprot-MAPRE1 »
Biogrid-MAPRE1 »
ProteomicsDB-MAPRE1 »

Tumorportal-MAPRE1 »
COSMIC-MAPRE1 »
GenomeRNAi-MAPRE1 »
Genecards-MAPRE1


Protein-protein Interactions for MAPRE1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKACB Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2A Cat. description Hein, Mann, Cell 2015
Category members IP bait GAS2L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TROAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAPRE1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CH-domain IPR001715 0.63
Category members EB1_C IPR004953 0


Protein complexes (CORUM database) featuring MAPRE1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAPRE1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0031253 cell projection membrane Database 0.6
Category members GO Category GO:0051010 microtubule plus-end binding Database 0.47
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members GO Category GO:0005819 spindle Database 0.41
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members Pathway Pathway_562 PID_NCADHERIN_PATHWAY 0 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0035372 protein localization to microtubule Database 0.23
Category members GO Category GO:0031115 negative regulation of microtubule polymerization Database 0.08
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0005881 cytoplasmic microtubule Database 0.04
Category members GO Category GO:0030981 cortical microtubule cytoskeleton Database 0
Category members GO Category GO:0035371 microtubule plus-end Database 0
Category members GO Category GO:0042995 cell projection Database 0


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