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Query: LZTR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LZTR1 0 -1.860 0.110 -0.960

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LZTR1 Ubiquitylation K101 0.120 _FDVK(gl)DCSWCR_
LZTR1 Ubiquitylation K484 -1.981 _LAQK(gl)LEQEAAPVPR_

Background Information for LZTR1:


Pubmed-LZTR1 »
Uniprot-LZTR1 »
Biogrid-LZTR1 »
ProteomicsDB-LZTR1 »

Tumorportal-LZTR1 »
COSMIC-LZTR1 »
GenomeRNAi-LZTR1 »
Genecards-LZTR1


Protein-protein Interactions for LZTR1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AIFM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF4A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KBTBD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUAK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUDT12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPSAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2O Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LZTR1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kelch_1 IPR006652 0.44
Category members BTB/POZ-like IPR000210 0.43
Category members BTB/POZ_fold IPR011333 0.36
Category members BTB_POZ IPR013069 0.32
Category members Kelch_2 IPR011498 0.2


Protein complexes (CORUM database) featuring LZTR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LZTR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members Disease phenotype Giant_cell_glioblastoma Giant cell glioblastoma Database 0.14
Category members Disease phenotype Gliosarcoma Gliosarcoma Database 0.14
Category members Disease phenotype Neurofibromatosis_type_3 Neurofibromatosis type 3 Database 0.08
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0009653 anatomical structure morphogenesis Database 0


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