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Query: LYST

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LYST 0 0.808 -0.570 0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LYST Phosphorylation S2124 0.490 0.108 _LTGS(ph)LGCSIDR_

Background Information for LYST:


Pubmed-LYST »
Uniprot-LYST »
Biogrid-LYST »
ProteomicsDB-LYST »

Tumorportal-LYST »
COSMIC-LYST »
GenomeRNAi-LYST »
Genecards-LYST


Protein-protein Interactions for LYST
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC9 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP85L Cat. description Hein, Mann, Cell 2015
Category members IP bait DAP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNC1LI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GAR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF1C Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait LLGL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH13 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPIA Cat. description Hein, Mann, Cell 2015
Category members IP bait SAP30 Cat. description Hein, Mann, Cell 2015
Category members IP bait TACC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNPO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VAMP2 Cat. description Hein, Mann, Cell 2015


Protein Domains in LYST
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members BEACH_dom IPR000409 0


Protein complexes (CORUM database) featuring LYST
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LYST
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0007017 microtubule-based process Database 0.3
Category members GO Category GO:0030595 leukocyte chemotaxis Database 0.17
Category members GO Category GO:0042832 defense response to protozoan Database 0.08
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members GO Category GO:0042742 defense response to bacterium Database 0.06
Category members GO Category GO:0002446 neutrophil mediated immunity Database 0.05
Category members GO Category GO:0032816 positive regulation of natural killer cell activation Database 0.04
Category members GO Category GO:0042267 natural killer cell mediated cytotoxicity Database 0.02
Category members GO Category GO:0002456 T cell mediated immunity Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0007040 lysosome organization Database 0
Category members GO Category GO:0032438 melanosome organization Database 0
Category members GO Category GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway Database 0
Category members GO Category GO:0033299 secretion of lysosomal enzymes Database 0
Category members GO Category GO:0033364 mast cell secretory granule organization Database 0
Category members GO Category GO:0043473 pigmentation Database 0
Category members GO Category GO:0048753 pigment granule organization Database 0
Category members GO Category GO:0055091 phospholipid homeostasis Database 0


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