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Query: LTA4H

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LTA4H 0 0.276 -1.370 1.580 -0.512 -2.457

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LTA4H Ubiquitylation K58 0.704 0.961 _SLVLDTK(gl)DLTIEK_
LTA4H Ubiquitylation K73 0.148 0.867 _VVINGQEVK(gl)YALGER_
LTA4H Ubiquitylation K519 -0.512 -0.452 _APLPLGHIK(gl)R_
LTA4H Ubiquitylation K337 -0.881 _LFGEK(gl)FR_

Background Information for LTA4H:





Protein-protein Interactions for LTA4H

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in LTA4H

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Peptidase_M1_C IPR015211 0.13
Category members Peptidase_M1_N IPR014782 0


Protein complexes (CORUM database) featuring LTA4H

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LTA4H

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004177 aminopeptidase activity Database 0.13
Category members Pathway Pathway_158 KEGG_ARACHIDONIC_ACID_METABOLISM 0 0.13
Category members GO Category GO:0004301 epoxide hydrolase activity Database 0.02
Category members GO Category GO:0008233 peptidase activity Database 0.02
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0006691 leukotriene metabolic process Database 0
Category members GO Category GO:0008237 metallopeptidase activity Database 0
Category members GO Category GO:0019369 arachidonic acid metabolic process Database 0
Category members GO Category GO:0019370 leukotriene biosynthetic process Database 0
Category members GO Category GO:0043171 peptide catabolic process Database 0


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