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Query: LRRC59

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LRRC59 0 2.351 -0.490 0.760 0.186 0.127 -1.028 0.061 -0.133

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LRRC59 Ubiquitylation K71 1.075 _LDLSK(gl)NK_
LRRC59 Ubiquitylation K73 0.595 1.075 _NK(gl)LQQLPADFGR_
LRRC59 Ubiquitylation K135 0.713 0.904 _VAGDCLDEK(gl)QCK_
LRRC59 Ubiquitylation K116 -0.769 _WLDLK(gl)DNPLDPVLAK_
LRRC59 Ubiquitylation K149 1.351 _VLQHMK(gl)AVQADQER_
LRRC59 Ubiquitylation K207 1.431 _EYDALK(gl)AAK_

Background Information for LRRC59:


Pubmed-LRRC59 »
Uniprot-LRRC59 »
Biogrid-LRRC59 »
ProteomicsDB-LRRC59 »

Tumorportal-LRRC59 »
COSMIC-LRRC59 »
GenomeRNAi-LRRC59 »
Genecards-LRRC59


Protein-protein Interactions for LRRC59
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH11 Cat. description Hein, Mann, Cell 2015
Category members IP bait SETD4 Cat. description Hein, Mann, Cell 2015
Category members IP bait ASPH Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LRRC59
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Leu-rich_rpt_typical-subtyp IPR003591 0.57
Category members Leu-rich_rpt IPR001611 0.32


Protein complexes (CORUM database) featuring LRRC59
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LRRC59
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61


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