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Query: LIN54

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LIN54 0 2.355 -1.290 1.530

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LIN54 Phosphorylation S186 0.379 0.446 _IAIS(ph)PLKS(ph)PNK_
LIN54 Phosphorylation S182 -0.976 -0.217 _IAIS(ph)PLKS(ph)PNK_

Background Information for LIN54:





Protein-protein Interactions for LIN54

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CAMK2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait L3MBTL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIN37 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIN9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYBL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUSC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LIN54

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CRC IPR005172 0


Protein complexes (CORUM database) featuring LIN54

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5589 LINC complex, S-phase Database 0.01
Category members Corum 5593 LINC core complex Database 0
Category members Corum 5596 LINC complex, quiescent cells Database 0


Categories featuring LIN54

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_313 REACTOME_MITOTIC_G1_G1_S_PHASES 0 1.45
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_869 REACTOME_G0_AND_EARLY_G1 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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