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Query: LETM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LETM1 0 1.078 0.530 -0.310 0.287 0.893 -0.656 0.206 0.348

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for LETM1:





Protein-protein Interactions for LETM1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6V0D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSD3B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LETM1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members LETM1 IPR011685 0.29
Category members EF_hand_dom IPR002048 0


Protein complexes (CORUM database) featuring LETM1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LETM1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members Disease phenotype Wolf-Hirschhorn_syndrome Wolf-Hirschhorn syndrome Database 0
Category members GO Category GO:0042407 cristae formation Database 0


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