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Query: LEMD2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LEMD2 0 2.536 0.610 -0.740 0.258 0.433

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LEMD2 Phosphorylation S497 0.821 _WTKPSS(ph)FSDSER_
LEMD2 Phosphorylation S501 0.450 0.658 _WTKPSSFSDS(ph)ER_
LEMD2 Phosphorylation S499 0.833 0.393 _WTKPSSFS(ph)DSER_
LEMD2 Ubiquitylation K264 0.191 _KTDEFCQAK(gl)QK_

Background Information for LEMD2:


Pubmed-LEMD2 »
Uniprot-LEMD2 »
Biogrid-LEMD2 »
ProteomicsDB-LEMD2 »

Tumorportal-LEMD2 »
COSMIC-LEMD2 »
GenomeRNAi-LEMD2 »
Genecards-LEMD2


Protein-protein Interactions for LEMD2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANO6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASPH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait B3GNT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRNA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRNA9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRNB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DLK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GDPD5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAUS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNA10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MME Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SGSM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC7A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPK1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VTN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LEMD2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members LEM_dom IPR003887 0.28
Category members LEM/LEM-like_dom IPR011015 0.28
Category members Inner-Nucl-membr_MAN1 IPR018996 0.04


Protein complexes (CORUM database) featuring LEMD2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LEMD2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0043409 negative regulation of MAPK cascade Database 0.87
Category members GO Category GO:0005639 integral to nuclear inner membrane Database 0.35
Category members GO Category GO:0035914 skeletal muscle cell differentiation Database 0


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