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Query: LAS1L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LAS1L 1 3.484 -0.760 0.900 -0.061 -0.108 -0.303 0.131 0.244

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LAS1L Phosphorylation S617 0.016 0.230 _MEVGPFSTGQES(ph)PTAENAR_
LAS1L Phosphorylation T619 0.155 _MEVGPFSTGQESPT(ph)AENAR_
LAS1L Ubiquitylation K263 2.192 0.054 _ALSHK(gl)ELYER_
LAS1L Phosphorylation S560 0.205 0.024 _AQQQEEQGS(ph)VNDVKEEEKEEK_
LAS1L Ubiquitylation K312 0.006 _VECVLAELK(gl)GVTCENR_
LAS1L Ubiquitylation K486 -0.235 _IIFK(gl)AMGQGLPDEEQEK_
LAS1L Ubiquitylation K292 -0.024 -0.559 _YLPK(gl)AIK_
LAS1L Ubiquitylation K295 -0.945 -0.992 _AIK(gl)AWNNPSPR_
LAS1L Ubiquitylation K499 -0.269 _AMGQGLPDEEQEK(gl)LLR_

Background Information for LAS1L:





Protein-protein Interactions for LAS1L

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015


Protein Domains in LAS1L

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring LAS1L

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5386 MLL1-WDR5 complex Database 0.31


Categories featuring LAS1L

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006364 rRNA processing Database 2.47
Category members GO Category GO:0071339 MLL1 complex Database 0.45


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