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Query: L2HGDH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
L2HGDH 0 0.045 1.410 -0.940 0.100 -0.055

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for L2HGDH:


Pubmed-L2HGDH »
Uniprot-L2HGDH »
Biogrid-L2HGDH »
ProteomicsDB-L2HGDH »

Tumorportal-L2HGDH »
COSMIC-L2HGDH »
GenomeRNAi-L2HGDH »
Genecards-L2HGDH


Protein-protein Interactions for L2HGDH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGB8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait L2HGDH Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in L2HGDH
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FAD-dep_OxRdtase IPR006076 0


Protein complexes (CORUM database) featuring L2HGDH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring L2HGDH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_10 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 0 1.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members Pathway Pathway_46 KEGG_BUTANOATE_METABOLISM 0 0
Category members GO Category GO:0006103 2-oxoglutarate metabolic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0031305 integral to mitochondrial inner membrane Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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