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Query: KRT18

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KRT18 1 4.882 0.450 -0.040 0.054 0.780 0.898

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KRT18 Phosphorylation S51 1.451 _S(ph)TSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDR_
KRT18 Phosphorylation T65 1.364 _STSFRGGMGSGGLAT(ph)GIAGGLAGMGGIQNEKETMQSLNDR_
KRT18 Phosphorylation S60 1.699 1.252 _STSFRGGM(ox)GS(ph)GGLATGIAGGLAGM(ox)GGIQNEK_

Background Information for KRT18:


Pubmed-KRT18 »
Uniprot-KRT18 »
Biogrid-KRT18 »
ProteomicsDB-KRT18 »

Tumorportal-KRT18 »
COSMIC-KRT18 »
GenomeRNAi-KRT18 »
Genecards-KRT18


Protein-protein Interactions for KRT18
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM83D Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015


Protein Domains in KRT18
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Keratin_I IPR002957 0
Category members IF IPR001664 0


Protein complexes (CORUM database) featuring KRT18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KRT18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0045095 keratin filament Database 0.35
Category members Pathway Pathway_961 PID_CASPASE_PATHWAY 0 0.19
Category members Disease phenotype CIRRHOSIS_FAMILIAL CIRRHOSIS FAMILIAL Database 0
Category members GO Category GO:0005882 intermediate filament Database 0
Category members GO Category GO:0009653 anatomical structure morphogenesis Database 0
Category members GO Category GO:0033209 tumor necrosis factor-mediated signaling pathway Database 0
Category members GO Category GO:0034451 centriolar satellite Database 0


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