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Query: KPNA6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KPNA6 1 2.857 -0.020 0.580
KPNA6 1 2.857 -0.020 0.580 0.537 0.237 0.200 0.316
KPNA6 1 2.857 -0.020 0.580 -1.917

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KPNA6 Ubiquitylation K49 0.560 0.382 _EQQLFK(gl)R_
KPNA6 Ubiquitylation K354 1.760 0.347 _K(gl)EACWTISNITAGNR_
KPNA6 Phosphorylation S6 0.450 0.219 _(ac)METMAS(ph)PGKDNYR_
KPNA6 Phosphorylation T3 0.131 _(ac)M(ox)ET(ph)MASPGKDNYR_
KPNA6 Phosphorylation S3 0.542 0.054 _(ac)AS(ph)PGKDNYR_
KPNA6 Ubiquitylation K134 -0.179 -0.102 _FVEFLK(gl)R_
KPNA6 Ubiquitylation K9 -0.089 -0.978 _(ac)METMASPGK(gl)DNYR_
KPNA6 Ubiquitylation K6 -0.649 _(ac)ASPGK(gl)DNYR_
KPNA6 Ubiquitylation K18 0.241 _SYK(gl)NNALNPEEMRR_

Background Information for KPNA6:


Pubmed-KPNA6 »
Uniprot-KPNA6 »
Biogrid-KPNA6 »
ProteomicsDB-KPNA6 »

Tumorportal-KPNA6 »
COSMIC-KPNA6 »
GenomeRNAi-KPNA6 »
Genecards-KPNA6


Protein-protein Interactions for KPNA6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK2AP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHD8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP2A Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait CTNNBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GSG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAST3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLF1IP Cat. description Hein, Mann, Cell 2015
Category members IP bait NAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait OXNAD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UFL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KBTBD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LMNA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MEAF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNMT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SREK1IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SURF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KPNA6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members HEAT IPR000357 3.83
Category members Armadillo IPR000225 1.58
Category members Importin-a_IBB IPR002652 0.44


Protein complexes (CORUM database) featuring KPNA6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KPNA6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006606 protein import into nucleus Database 1.81
Category members GO Category GO:0006607 NLS-bearing protein import into nucleus Database 1.48
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0060135 maternal process involved in female pregnancy Database 0


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