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Query: KPNA5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KPNA5 1 1.574 2.680 -1.040
KPNA5 1 1.574 2.680 -1.040 0.537 0.237 0.200 0.316
KPNA5 1 1.574 2.680 -1.040 -0.148 -0.215 0.756 -0.024 -0.936

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KPNA5 Phosphorylation S3 0.542 0.054 _(ac)AS(ph)PGKDNYR_
KPNA5 Ubiquitylation K46 -0.562 -0.121 _EEQLFK(gl)R_

Background Information for KPNA5:


Pubmed-KPNA5 »
Uniprot-KPNA5 »
Biogrid-KPNA5 »
ProteomicsDB-KPNA5 »

Tumorportal-KPNA5 »
COSMIC-KPNA5 »
GenomeRNAi-KPNA5 »
Genecards-KPNA5


Protein-protein Interactions for KPNA5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KBTBD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNMT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SREK1IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KPNA5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members HEAT IPR000357 3.83
Category members Armadillo IPR000225 1.58
Category members Importin-a_IBB IPR002652 0.44


Protein complexes (CORUM database) featuring KPNA5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KPNA5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_689 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 0 3.51
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0006606 protein import into nucleus Database 1.81
Category members GO Category GO:0006607 NLS-bearing protein import into nucleus Database 1.48
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0008565 protein transporter activity Database 0.26


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