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Query: KLHL12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KLHL12 0 -0.318 -0.090 0.700 -1.351 -0.469

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KLHL12 Ubiquitylation K256 -0.549 _DLVDEAK(gl)K_
KLHL12 Ubiquitylation K257 -0.549 _DLVDEAK(gl)K_

Background Information for KLHL12:


Pubmed-KLHL12 »
Uniprot-KLHL12 »
Biogrid-KLHL12 »
ProteomicsDB-KLHL12 »

Tumorportal-KLHL12 »
COSMIC-KLHL12 »
GenomeRNAi-KLHL12 »
Genecards-KLHL12


Protein-protein Interactions for KLHL12
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP170P1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait EWSR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MED12 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMM50 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLHL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KLHL12
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kelch_1 IPR006652 0.44
Category members BTB/POZ-like IPR000210 0.43
Category members BACK IPR011705 0.43
Category members BTB/POZ_fold IPR011333 0.36
Category members BTB_POZ IPR013069 0.32
Category members Kelch-like_gigaxonin-typ IPR017096 0.23
Category members Kelch_2 IPR011498 0.2


Protein complexes (CORUM database) featuring KLHL12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KLHL12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_671 PID_WNT_CANONICAL_PATHWAY 0 0.64
Category members GO Category GO:0006888 ER to Golgi vesicle-mediated transport Database 0.28
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0006513 protein monoubiquitination Database 0
Category members GO Category GO:0030134 ER to Golgi transport vesicle Database 0
Category members GO Category GO:0031463 Cul3-RING ubiquitin ligase complex Database 0
Category members GO Category GO:0048208 COPII vesicle coating Database 0


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