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Query: KLC3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KLC3 0 0.228 0.470 -1.230

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KLC3 Phosphorylation S466 0.017 0.211 _AMS(ph)LNTLNVDAPR_

Background Information for KLC3:


Pubmed-KLC3 »
Uniprot-KLC3 »
Biogrid-KLC3 »
ProteomicsDB-KLC3 »

Tumorportal-KLC3 »
COSMIC-KLC3 »
GenomeRNAi-KLC3 »
Genecards-KLC3


Protein-protein Interactions for KLC3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CETN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIAA1279 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF5B Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait NDC80 Cat. description Hein, Mann, Cell 2015
Category members IP bait C19orf46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KLC3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members Rabaptin_Rab5-bd_dom IPR015390 0.21
Category members Kinesin_light IPR002151 0.16


Protein complexes (CORUM database) featuring KLC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KLC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members Pathway Pathway_1314 REACTOME_KINESINS 0 0.32
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0035253 ciliary rootlet Database 0.03
Category members GO Category GO:0019894 kinesin binding Database 0.02
Category members GO Category GO:0008088 axon cargo transport Database 0
Category members GO Category GO:0031514 motile cilium Database 0


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